Understanding
Hyperbaric Oxygen Therapy

Learn how HBOT is used in clinical settings and where it may be available.

How It Really Works (Simply Put)

Think of your body like a city.
Your blood vessels are the roads, and oxygen is the supply truck.

Under normal conditions, those trucks stay on the highways.

Hyperbaric oxygen therapy changes that — delivering oxygen beyond the main roads and into areas that weren't getting it before.

That's where healing starts.

How HBOT Works

What Is Hyperbaric Oxygen Therapy (HBOT)?

Every cell in your body requires oxygen to heal, fight infection, and function optimally. However, chronic inflammation, injuries, and systemic diseases often create hypoxia—a state where your tissues simply cannot get enough oxygen from normal breathing.

Hyperbaric Oxygen Therapy (HBOT) solves this at the cellular level. By breathing 100% pure oxygen in a pressurized chamber, your blood plasma becomes super-saturated with oxygen. This hyper-oxygenated plasma then travels deep into tissues, bones, and the brain, reaching areas that normal red blood cells cannot.

The Result?

  • Reduced inflammation
  • Support for tissue repair
  • A systemic environment where your body can repair itself

The Power of Pressurized Oxygen

Hyperbaric oxygen therapy (HBOT) delivers concentrated oxygen in a pressurized environment, allowing oxygen to dissolve directly into the bloodstream, plasma, and other body fluids. This unique process dramatically increases oxygen delivery to tissues that are injured, inflamed, or oxygen-deprived — enabling the body to accelerate its natural healing processes.

Under these enhanced conditions, oxygen reaches areas where normal circulation may be limited, stimulating new blood vessel growth, reducing inflammation, and supporting the body's immune response.

Erythrocyte 3D illustration showing red blood cells transporting oxygen throughout the bloodstream
Clinical Evidence

Research & Clinical Foundation

Hyperbaric oxygen therapy is supported by decades of clinical research and FDA-cleared indications.

FDA-Cleared Indications

HBOT is FDA-cleared for 14 conditions including diabetic wounds, radiation injury, crushed bones, burns, and more.

60+ Years of Research

HBOT has been studied extensively since the 1940s with thousands of peer-reviewed publications demonstrating safety and efficacy.

Insurance Coverage

Medicare, Medicaid, and major private insurers cover HBOT for FDA-cleared indications—streamlining patient access.

Clinical Guidelines

HBOT is included in treatment guidelines from wound care societies, undersea medicine associations, and emergency protocols.

Safety Profile

HBOT has a strong safety record when operated by trained professionals following established protocols and safety standards.

RxAir360 Clinical Plan

Our 510(k) submission includes comprehensive safety and performance testing aligned with FDA guidance for hyperbaric devices.

References: UHMS Guidelines, FDA 510(k) Database, CMS Coverage Determinations, Peer-Reviewed Literature

Free Resource

HBOT Clinical Reference Guide

A comprehensive clinical overview of Hyperbaric Oxygen Therapy, designed for healthcare professionals, patients, and advocates seeking evidence-based information.

  • FDA-cleared indications and clinical applications
  • Peer-reviewed research overview and clinical evidence
  • Insurance coverage considerations and patient access
  • Questions to discuss with your healthcare provider
Download the HBOT Guide
Book cover for The HBOT 95 by RADx360 Inc, promoting a guide to 95 conditions treated with hyperbaric oxygen therapy

This guide is provided for educational purposes. HBOT should only be administered under the supervision of a licensed healthcare professional. Consult your physician to determine whether HBOT is appropriate for your condition.

Patient Stories

What Patients Are Saying

Real experiences from patients who have benefited from hyperbaric oxygen therapy.

* These testimonials reflect individual patient experiences with hyperbaric oxygen therapy administered at separately licensed and cleared HBOT facilities. These patients were not treated with the RxAir360 chamber, which has not yet received FDA 510(k) clearance and is not currently available for clinical use or sale. Individual results may vary. HBOT should only be administered under the supervision of a licensed healthcare professional. Consult your physician to determine whether HBOT is appropriate for your condition.